It happened on Keele Street north of Wilson Avenue at around 1:30 p.m.
According to police, the vehicle struck a hydro pole and rolled, coming to rest on top of a second parked vehicle.
Wires were down in the area as a result, Toronto EMS said.
One patient, described by paramedics as an elderly man, was extricated from the vehicle and transported to hospital with serious to life-threatening injuries.
Keele Street was closed in both directions from Wilson Avenue to Calvington Drive for several hours. It reopened shortly before 9 p.m.
We hope that the person in hospital gets well soon and that no residents were affected by any outage or blackout.
Sources / More info: CP24